{"filing": {"accession": "0001062822-26-000050", "cik": "0001062822", "ticker": "LXRX", "company_name": "LEXICON PHARMACEUTICALS, INC.", "form_type": "10-K", "filing_type": "10-K", "filing_date": "2026-03-05", "accepted_datetime": null, "acceptance_datetime": null, "accepted_at": null, "primary_doc_url": "https://www.sec.gov/Archives/edgar/data/1062822/000106282226000050/0001062822-26-000050-index.htm", "filing_url": "https://www.sec.gov/Archives/edgar/data/1062822/000106282226000050/0001062822-26-000050-index.htm", "period_of_report": "2025-12-31"}, "html_url": "/api/filings/000106282226000050/stream", "exhibits": [], "sections": [{"section_name": "item_1a", "section_title": "Risk Factors", "start_position": 6880, "end_position": 7549}, {"section_name": "item_1", "section_title": "Business", "start_position": 7549, "end_position": 180472}, {"section_name": "item_1b", "section_title": "Unresolved Staff Comments", "start_position": 180472, "end_position": 180511}, {"section_name": "item_1c", "section_title": "Cybersecurity", "start_position": 180511, "end_position": 186395}, {"section_name": "item_2", "section_title": "Properties", "start_position": 186395, "end_position": 187187}, {"section_name": "item_3", "section_title": "Legal Proceedings", "start_position": 187187, "end_position": 187566}, {"section_name": "item_4", "section_title": "Mine Safety Disclosures", "start_position": 187566, "end_position": 187621}, {"section_name": "item_5", "section_title": "Market for Registrant's Common Equity", "start_position": 187621, "end_position": 189441}, {"section_name": "item_7", "section_title": "Management's Discussion and Analysis", "start_position": 189441, "end_position": 221690}, {"section_name": "item_7a", "section_title": "Quantitative and Qualitative Disclosures", "start_position": 221690, "end_position": 221956}, {"section_name": "item_8", "section_title": "Financial Statements", "start_position": 221956, "end_position": 222088}, {"section_name": "item_9a", "section_title": "Controls and Procedures", "start_position": 222208, "end_position": 224389}, {"section_name": "item_9b", "section_title": "Other Information", "start_position": 224389, "end_position": 224786}, {"section_name": "item_10", "section_title": "Directors and Executive Officers", "start_position": 224786, "end_position": 225423}, {"section_name": "item_11", "section_title": "Executive Compensation", "start_position": 225423, "end_position": 226189}, {"section_name": "item_12", "section_title": "Security Ownership", "start_position": 226189, "end_position": 226750}, {"section_name": "item_13", "section_title": "Certain Relationships", "start_position": 226750, "end_position": 227248}, {"section_name": "item_14", "section_title": "Principal Accountant Fees", "start_position": 227248, "end_position": 238329}, {"section_name": "item_16", "section_title": "Form 10-K Summary", "start_position": 238329, "end_position": 313338}], "tables": [{"table_index": 0, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 1, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 2, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 3, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 4, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 5, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 6, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 7, "table_type": "exhibit_index", "caption": null, "header_text": ""}, {"table_index": 8, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 9, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 10, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 11, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 12, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 13, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 14, "table_type": "exhibit_index", "caption": null, "header_text": ""}, {"table_index": 15, "table_type": "exhibit_index", "caption": null, "header_text": ""}, {"table_index": 16, "table_type": "exhibit_index", "caption": null, "header_text": ""}, {"table_index": 17, "table_type": "exhibit_index", "caption": null, "header_text": ""}, {"table_index": 18, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 19, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 20, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 21, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 22, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 23, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 24, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 25, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 26, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 27, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 28, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 29, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 30, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 31, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 32, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 33, "table_type": "financial", "caption": null, "header_text": ""}, {"table_index": 34, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 35, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 36, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 37, "table_type": "text", "caption": null, "header_text": ""}, {"table_index": 38, "table_type": "financial", "caption": null, "header_text": ""}], "exhibits_pending": true, "cdn_html": true, "response_time_ms": 25}